Low Lung Function in Middle-Aged Smokers Impacts Health Status, Morbidities, and Mortality: An Observational Analysis of the Lovelace Smokers Cohort

Smokers with LLF without airflow obstruction exhibited reduced survival and an increased risk for development of chronic morbidities. Thus, spirometry may be used to identify at-risk individuals, allowing for early preventative interventions that can improve long-term health outcomes. <i>Take home message:</i> Among ever smokers without airflow obstruction, LLF is associated with increased mortality and poor health status. Spirometry may identify at-risk patients, enabling early emphasis on interventions with the potential to improve long-term health outcomes.

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Publication Details

Journal
Chronic Obstructive Pulmonary Diseases Journal of the COPD Foundation
Published
2025-01-01
DOI
https://doi.org/10.15326/jcopdf.2025.0605
Primary Topic
Chronic Obstructive Pulmonary Disease (COPD) Research
Type
article
Field-Weighted Citation Impact
0.00

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article

Low Lung Function in Middle-Aged Smokers Impacts Health Status, Morbidities, and Mortality: An Observational Analysis of the Lovelace Smokers Cohort

Bartolomé R. Celli, Ventzislava A. Hristova, Kristoffer Ostridge, Congjian Liu et al.
Chronic Obstructive Pulmonary Diseases Journal of the COPD Foundation
Chronic Obstructive Pulmonary Disease (COPD) Research
article

Low Lung Function in Middle-Aged Smokers Impacts Health Status, Morbidities, and Mortality: An Observational Analysis of the Lovelace Smokers Cohort

Bartolomé R. Celli, Ventzislava A. Hristova, Kristoffer Ostridge, Congjian Liu, François-Xavier Blé, Maria A. Picchi, Yohannes Tesfaigzi, Darlene Harbour, Mehul Patel, Steven A. Belinsky, Mary N. Brown, Paul Dorinsky
article en

Abstract

Smokers with LLF without airflow obstruction exhibited reduced survival and an increased risk for development of chronic morbidities. Thus, spirometry may be used to identify at-risk individuals, allowing for early preventative interventions that can improve long-term health outcomes. <i>Take home message:</i> Among ever smokers without airflow obstruction, LLF is associated with increased mortality and poor health status. Spirometry may identify at-risk patients, enabling early emphasis on interventions with the potential to improve long-term health outcomes.

Chronic Obstructive Pulmonary Diseases Journal of the COPD FoundationVol. 12(5)
AstraZeneca (United Kingdom) (GB), Lovelace Respiratory Research Institute (US), Massachusetts General Hospital (US), AstraZeneca (Brazil) (BR), AstraZeneca (Japan) (JP), Lovelace Medical Center (US), AstraZeneca (Finland) (FI), AstraZeneca (Spain) (ES), Lovelace Health System (US), University of Southampton (GB)
AstraZeneca
Good health and well-being
Openalex Percentile: Top 71%
Chronic Obstructive Pulmonary Disease (COPD) Research
DOIOpen Access PDFOpenAlex
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