Effects of sildenafil and metformin on endothelin-1 in the progression of pulmonary hypertension
Sildenafil and metformin alone or in combination improve mPAP and ET-1 levels. Sildenafil plus metformin prevents artery remodeling in the PH model.
Authors
- Mahrus A. Rahman (ORCID: https://orcid.org/0000-0001-5129-457X)
- Agus Cahyono
- Widjiati Widjiati (ORCID: https://orcid.org/0000-0002-8376-1176)
- Irwanto Irwanto (ORCID: https://orcid.org/0009-0005-3237-081X)
Institutions
- University of Surabaya (ID)
- Universitas Airlangga (ID)
Publication Details
- Journal
- Open Veterinary Journal
- Published
- 2025-01-01
- DOI
- https://doi.org/10.5455/ovj.2025.v15.i7.20
- Primary Topic
- Pulmonary Hypertension Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00