Insulin Like Growth Factor 1 and Estrogen from Cumulus cell culture increase the success of in vitro fertilization in cattle
In summary, the monolayer culture of bovine cumulus cells generated IGF-1 and estrogen, which functioned as mitogenic agents, positively influencing IVF outcomes and embryo development while significantly decreasing apoptosis in the embryos.
Authors
- Adeyinka Oye Akintunde (ORCID: https://orcid.org/0000-0002-6013-0902)
- Imam Mustofa (ORCID: https://orcid.org/0000-0003-4543-1659)
- Ulvi Fitri Handayani (ORCID: https://orcid.org/0000-0001-9443-2901)
- Aswin Rafif Khairullah (ORCID: https://orcid.org/0000-0001-9421-9342)
- Riza Zainuddin Ahmad (ORCID: https://orcid.org/0000-0002-2067-717X)
- Pudji Srianto (ORCID: https://orcid.org/0000-0002-6832-9799)
- Sri Mulyati (ORCID: https://orcid.org/0000-0002-4115-3519)
- Tita Damayanti Lestari (ORCID: https://orcid.org/0000-0001-8561-3452)
- Latifah Latifah (ORCID: https://orcid.org/0000-0003-0667-3532)
- Fedik Abdul Rantam (ORCID: https://orcid.org/0000-0002-1047-2410)
- Lili Anggraini
- Bima Putra Pratama (ORCID: https://orcid.org/0000-0002-9979-6648)
Institutions
- Universitas Airlangga (ID)
- Indonesian Agency for Agricultural Research and Development (ID)
- National Research and Innovation Agency (ID)
Publication Details
- Journal
- Open Veterinary Journal
- Published
- 2025-01-01
- DOI
- https://doi.org/10.5455/ovj.2025.v15.i7.13
- Primary Topic
- Reproductive Biology and Fertility
- Type
- article
- Field-Weighted Citation Impact
- 0.00