Access to chiral α-methyl-α-aryl carboxylic acids <i>via</i> phosphoric acid-catalyzed kinetic resolution of biaryl oxazepines
A chiral phosphoric acid-catalyzed kinetic resolution of racemic biaryl oxazepines with alcohols was developed, which afforded biaryl oxazepines and imidates bearing a chiral center in high enantioselectivities.
Authors
- Liejin Zhou (ORCID: https://orcid.org/0000-0003-3929-2525)
- Shi‐Chao Ren (ORCID: https://orcid.org/0000-0003-4248-6021)
- Wenyue Tan (ORCID: https://orcid.org/0000-0001-5449-7313)
- Bowen Zhu (ORCID: https://orcid.org/0000-0003-2350-2735)
- Yifei Ma
- Xing Yang (ORCID: https://orcid.org/0009-0002-3031-6746)
- Zhikang Wei
- Guo Dai
- Ting Tu
Institutions
- Zhejiang Normal University (CN)
- Hunan Normal University (CN)
- Guizhou University (CN)
Publication Details
- Journal
- Organic Chemistry Frontiers
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5qo00953g
- Primary Topic
- Asymmetric Synthesis and Catalysis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Education Department of Hunan Province
- National Natural Science Foundation of China
- Hunan Normal University
- Hunan Provincial Science and Technology Department
- Natural Science Foundation of Hunan Province