Mediastinoscopy-Assisted Esophagectomy as an Effective Treatment for IgG4-Related Esophageal Stenosis: A Case Report

This case underscores that IgG4-RD should be considered in the differential diagnosis of refractory esophageal stenosis, even with initially inconclusive biopsies. While serum IgG4 measurement has low sensitivity, it is still recommended. For benign esophageal stenosis of unclear etiology, particularly in patients with significant comorbidities, MAE can be a useful and potentially curative surgical option, offering symptom resolution and the possibility of a drug-free outcome.

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Publication Details

Journal
Surgical Case Reports
Published
2025-01-01
DOI
https://doi.org/10.70352/scrj.cr.25-0346
Citations
2
Primary Topic
Esophageal and GI Pathology
Type
article
Field-Weighted Citation Impact
4.01
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article

Mediastinoscopy-Assisted Esophagectomy as an Effective Treatment for IgG4-Related Esophageal Stenosis: A Case Report

Takehito Yamamoto, Masahiro Maeda, Keiko Kasahara, Mitsuhiro Nikaido et al.
2 citations
Surgical Case Reports
Esophageal and GI Pathology
4.01
article

Mediastinoscopy-Assisted Esophagectomy as an Effective Treatment for IgG4-Related Esophageal Stenosis: A Case Report

Takehito Yamamoto, Masahiro Maeda, Keiko Kasahara, Mitsuhiro Nikaido, Ryosuke Okamura, Shigeo Hisamori, Shigeru Tsunoda, Yuki Teramoto, Yoshiro Itatani, Masazumi Sakaguchi, Kazutaka Obama, Shintaro Okumura, Ryuhei Aoyama, Koya Hida, Nobuaki Hoshino, Shoichi Kitano, Masahiro Hara, Takashi Sakamoto, Kohei Ueno, Yu Yoshida
article en
2 citations

Abstract

This case underscores that IgG4-RD should be considered in the differential diagnosis of refractory esophageal stenosis, even with initially inconclusive biopsies. While serum IgG4 measurement has low sensitivity, it is still recommended. For benign esophageal stenosis of unclear etiology, particularly in patients with significant comorbidities, MAE can be a useful and potentially curative surgical option, offering symptom resolution and the possibility of a drug-free outcome.

Surgical Case ReportsVol. 11(1)
Kyoto University (JP), Tenri Hospital (JP)
Good health and well-being
Openalex Percentile: Top 6%
Esophageal and GI Pathology
4.01
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