Nanomedicine breakthroughs in cancer and neurodegenerative disease therapy

Cancer is a significant medical concern that presents a substantial risk to the holistic health of persons. Moreover, afflictions affecting the central nervous system, including neurodegenerative disorders, offer a significant peril to the well-being of the general population and necessitate immediate scholarly focus. Brain cancer and Alzheimer's disease pose substantial treatment challenges due to the formidable task of effectively delivering medication over the protective fluid barrier of the brain. Compared to conventional medicine, nanotechnology-based treatments are more secure, effective, and selective in targeting molecular and cellular processes. The optimization of cancer treatment is an ongoing process driven by advancements in established treatment procedures and the emergence of novel therapeutic modalities. Nanomedicine plays a significant part in the progress of tumor therapy techniques. This article presents an in-depth review of the various applications of nanomedicine in the realms of chemotherapy, gene therapy, and immunotherapy. In light of prevailing challenges, including sub-optimal specificity of first-line chemotherapy agents, susceptibility of nucleic acid drugs to degradation, and frequent occurrence of negative symptoms associated with the immune system in immunotherapy, this discourse explores the potential integration of nanomedicine with these therapeutic approaches. The discussion encompasses illustrative instances and highlights the benefits associated with using nanomedicine. • Nanomedicine aids brain drug delivery, overcoming the blood-brain barrier. • Advances in nanomedicine enhance chemotherapy, gene therapy, and immunotherapy. • Nanotech tackles chemo specificity, nucleic acid stability, and immune side effects. • Targeted drug delivery via nanotech minimizes toxicity and boosts treatment efficacy. • Future trends highlight role of nanomedicine in oncology and neurology therapies.

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Publication Details

Journal
Next Nanotechnology
Published
2025-01-01
DOI
https://doi.org/10.1016/j.nxnano.2025.100233
Citations
2
Primary Topic
Nanoparticle-Based Drug Delivery
Type
article
Field-Weighted Citation Impact
1.19
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article

Nanomedicine breakthroughs in cancer and neurodegenerative disease therapy

Rayees Ul Islam, Swaleha Naseem, Ashraful Haque, Tariq Hayat Khan
2 citations
Next Nanotechnology
Nanoparticle-Based Drug Delivery
1.19
article

Nanomedicine breakthroughs in cancer and neurodegenerative disease therapy

Rayees Ul Islam, Swaleha Naseem, Ashraful Haque, Tariq Hayat Khan
article en
2 citations

Abstract

Cancer is a significant medical concern that presents a substantial risk to the holistic health of persons. Moreover, afflictions affecting the central nervous system, including neurodegenerative disorders, offer a significant peril to the well-being of the general population and necessitate immediate scholarly focus. Brain cancer and Alzheimer's disease pose substantial treatment challenges due to the formidable task of effectively delivering medication over the protective fluid barrier of the brain. Compared to conventional medicine, nanotechnology-based treatments are more secure, effective, and selective in targeting molecular and cellular processes. The optimization of cancer treatment is an ongoing process driven by advancements in established treatment procedures and the emergence of novel therapeutic modalities. Nanomedicine plays a significant part in the progress of tumor therapy techniques. This article presents an in-depth review of the various applications of nanomedicine in the realms of chemotherapy, gene therapy, and immunotherapy. In light of prevailing challenges, including sub-optimal specificity of first-line chemotherapy agents, susceptibility of nucleic acid drugs to degradation, and frequent occurrence of negative symptoms associated with the immune system in immunotherapy, this discourse explores the potential integration of nanomedicine with these therapeutic approaches. The discussion encompasses illustrative instances and highlights the benefits associated with using nanomedicine. • Nanomedicine aids brain drug delivery, overcoming the blood-brain barrier. • Advances in nanomedicine enhance chemotherapy, gene therapy, and immunotherapy. • Nanotech tackles chemo specificity, nucleic acid stability, and immune side effects. • Targeted drug delivery via nanotech minimizes toxicity and boosts treatment efficacy. • Future trends highlight role of nanomedicine in oncology and neurology therapies.

Next NanotechnologyVol. 8
Aligarh Muslim University (IN)
Openalex Percentile: Top 21%
Nanoparticle-Based Drug Delivery
1.19
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