Profile of Adherence to Treatment of Latent Tuberculosis Infection in users Treated in a Location in the city of Salvador, Bahia, Brazil.

Introduction: The high prevalence and incidence of LTBI in the world means that the disease has not yet been eradicated. Even though the treatment is already consolidated, few studies on drug adherence in LTBI have been developed. This study investigates adherence to pharmacological treatment of LTBI in users treated at health units in a location in Salvador, Bahia, Brazil. Methods: observational cross-sectional study, using a sociodemographic and clinical questionnaire and an adapted Morisky -Green adherence test. Results: 34 patients with LTBI participated. The majority of users adhere to pharmacotherapy (82.4%; N=24). And a small number are few adherents 17.6% (N=6). No non-compliant users were found. Adherence to LTBI treatment is related to selected sociodemographic and clinical variables: appearance of ADRs (p =0.031); difficulties in taking medications (p=0.020); and participation in tuberculosis groups (p =0.043). Conclusion: there is a need to better conduct LTBI treatment in the Salvador Railway Suburb. F uture research is valid to deepen this study. A protocol and/or flow is suggested to promote adherence of people with LTBI.

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Publication Details

Journal
International Journal of Clinical Case Reports and Reviews
Published
2025-07-30
DOI
https://doi.org/10.31579/2690-4861/792
Primary Topic
Health Education and Validation
Type
article
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article

Profile of Adherence to Treatment of Latent Tuberculosis Infection in users Treated in a Location in the city of Salvador, Bahia, Brazil.

M Ramos
International Journal of Clinical Case Reports and Reviews
Health Education and Validation
article

Profile of Adherence to Treatment of Latent Tuberculosis Infection in users Treated in a Location in the city of Salvador, Bahia, Brazil.

M Ramos
article en

Abstract

Introduction: The high prevalence and incidence of LTBI in the world means that the disease has not yet been eradicated. Even though the treatment is already consolidated, few studies on drug adherence in LTBI have been developed. This study investigates adherence to pharmacological treatment of LTBI in users treated at health units in a location in Salvador, Bahia, Brazil. Methods: observational cross-sectional study, using a sociodemographic and clinical questionnaire and an adapted Morisky -Green adherence test. Results: 34 patients with LTBI participated. The majority of users adhere to pharmacotherapy (82.4%; N=24). And a small number are few adherents 17.6% (N=6). No non-compliant users were found. Adherence to LTBI treatment is related to selected sociodemographic and clinical variables: appearance of ADRs (p =0.031); difficulties in taking medications (p=0.020); and participation in tuberculosis groups (p =0.043). Conclusion: there is a need to better conduct LTBI treatment in the Salvador Railway Suburb. F uture research is valid to deepen this study. A protocol and/or flow is suggested to promote adherence of people with LTBI.

International Journal of Clinical Case Reports and ReviewsVol. 28(02)
Openalex Percentile: Top 79%
Health Education and Validation
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Profile of Adherence to Treatment of Latent Tuberculosis Infection in users Treated in a Location in the city of Salvador, Bahia, Brazil. — M Ramos · International Journal of Clinical Case Reports and Reviews (2025) | TGRS Research Map | TGRS