A NAD(P)H-driven mitochondria-to-nucleus probe for dual-organelle imaging in dopaminergic toxicity models
A novel dual-functional fluorescent probe was developed enabling real-time tracking of intracellular NAD(P)H flux and mitochondrial functional decline at the single-cell level with high precision. This probe could assess mitochondrial damage and energy metabolism disruptions in PD-related dopaminergic toxicity models.
Authors
- Bin Jiang (ORCID: https://orcid.org/0000-0002-7453-828X)
- Majun Yang
- Yuling Qin (ORCID: https://orcid.org/0000-0003-2819-8592)
- Li Wu (ORCID: https://orcid.org/0000-0002-4118-7970)
- Qi Wang (ORCID: https://orcid.org/0000-0002-9817-0643)
- Jiayun Guan
- Qu Tang
Institutions
- Nantong University (CN)
Publication Details
- Journal
- Chemical Communications
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5cc03654b
- Citations
- 1
- Primary Topic
- Photoreceptor and optogenetics research
- Type
- article
- Field-Weighted Citation Impact
- 0.91