Method for Simultaneous Determination of Amino Acid Surfactants Sodium N-Lauroylsarcosinate and Sodium Methyl Cocoyl Taurate in Personal Care Products, by Using High Performance Liquid Chromatography
Sodium N-lauroylsarcosinate (NLS) and sodium methyl cocoyl taurate (SMCT) are widely used in sulfate free personal care products. We present a straightforward and highly sensitive High-Performance Liquid Chromatographic (HPLC) method for simultaneous detection and estimation of these substances in commercial personal care products. The HPLC method has a detection limit for NLS of concentrations as low as 1.5 ppm, and that for SMCT of 4.0 ppm, all with a signal-to-noise (S/N) ratio exceeding 3.0. Additionally, the method enables quantification down to 4.5 ppm for NLS, and 12.0 ppm for SMCT, with an S/N ratio surpassing 10.0. This validated method serves as a versatile tool for the accurate quantification of NLS, and SMCT in sulfate free personal care products like shampoos, face washes, body washes, baby shampoos, and toothpastes.
Authors
- Kumar Thangarathinam
- Udhayachandran Narayanan
Publication Details
- Journal
- Journal of Chromatographic Science
- Published
- 2025-07-14
- DOI
- https://doi.org/10.1093/chromsci/bmaf044
- Primary Topic
- Analytical Chemistry and Chromatography
- Type
- article
- Field-Weighted Citation Impact
- 0.00