Immune microenvironment heterogeneity characterizes biologically distinct KRAS<sup>mut</sup>/SPOP<sup>mut</sup> and KRAS<sup>mut</sup>/PIK3CA<sup>mut</sup> mesonephric-like adenocarcinoma subtypes revealed by integrated whole-exome and transcriptomic
This is the first study to demonstrate the comprehensive molecular characteristics of MLA and detect biologically distinct subtypes of <i>KRAS</i> <sup>mut</sup>/<i>SPOP</i> <sup>mut</sup> and <i>KRAS</i> <sup>mut</sup>/<i>PIK3CA</i> <sup>mut</sup> MLAs.
Authors
- Kemin Li (ORCID: https://orcid.org/0000-0001-8731-5846)
- Lian Xu (ORCID: https://orcid.org/0000-0002-6374-7342)
- Qingbo Wei (ORCID: https://orcid.org/0000-0002-3577-5661)
- Rutie Yin (ORCID: https://orcid.org/0000-0002-9221-6727)
- Wei Wang (ORCID: https://orcid.org/0000-0003-2642-3338)
- Jing Zeng (ORCID: https://orcid.org/0009-0009-1713-9993)
- Kaixuan Yang
- Jin Wang (ORCID: https://orcid.org/0009-0006-3212-8326)
- Lu Yang (ORCID: https://orcid.org/0009-0005-3974-4466)
- Changbin Zhu
- Qingli Li (ORCID: https://orcid.org/0000-0002-2290-4532)
Institutions
- Sichuan University (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-01-01
- DOI
- https://doi.org/10.3389/fimmu.2025.1605227
- Primary Topic
- T-cell and B-cell Immunology
- Type
- article
- Field-Weighted Citation Impact
- 0.00