Highly genetically diverse variants of hepatitis C virus still predominate in Cameroon but with low frequency of mutations associated to resistance of NS5B polymerase-targeted antivirals
Genotype 5 was identified for the first time in Cameroon. The frequency of V321I and C316H/N polymorphism with unknown impact on NS5B polymerase inhibitors is increasing in Cameroon.
Authors
- Henry Namme Luma (ORCID: https://orcid.org/0000-0003-2388-477X)
- Laure Tchapda
- Oudou Njoya
- Nadège Mafopa Goumkwa
- Fokunang Charles (ORCID: https://orcid.org/0000-0003-1214-9155)
- Clauvis Kunkeng Yengo (ORCID: https://orcid.org/0000-0001-7579-9708)
- Mathurin Kowo (ORCID: https://orcid.org/0000-0001-9055-6165)
- Judith Torimiro (ORCID: https://orcid.org/0000-0003-3844-8428)
- Patrick Awoumou (ORCID: https://orcid.org/0000-0003-4138-0399)
- Alliance-Laure Otam
- Cindy Lobe (ORCID: https://orcid.org/0000-0001-9659-0049)
- Marie Claire Assoumou Okomo
- Signang Alberic Ndonku
- Junior Ekunidi Engarimbi
- Fabrice Levoa Eteme
- Diapa Nana Yannick
- Marie-Ange Kwizera
- Inoussa Pempeme
- Williams Anderson Ngameleu
Institutions
- Université de Yaoundé I (CM)
- University of Buea (CM)
- University of Douala (CM)
- Centre International De Reference Chantal Biya (CM)
- National Public Health Laboratory (NP)
- Ministry of Public Health (CM)
- University Teaching Hospital of Yaounde (CM)
- University of Ngaoundéré (CM)
Publication Details
- Journal
- JAC-Antimicrobial Resistance
- Published
- 2025-06-20
- DOI
- https://doi.org/10.1093/jacamr/dlaf114
- Primary Topic
- Hepatitis C virus research
- Type
- article
- Field-Weighted Citation Impact
- 0.00