Specific changes in intestinal microbiota in various forms of autoimmune arthritis: from pathogenesis to therapy

This study investigates the role of the intestinal microbiome in the development of autoimmune arthritides, including rheumatoid arthritis (RA), psoriatic arthritis (PsA), and ankylosing spondylitis (AS). A comparative analysis of gut microbiota composition was performed in 120 patients with various forms of arthritis and 40 healthy volunteers. Using 16S rRNA gene sequencing, disease-specific alterations were identified: a significant increase in Prevotella copri up to 18.3% in RA, predominance