Recurrent course of two subtypes of retroperitoneal liposarcomas with development of end-stage hydronephrosis: a rare case report

Hydronephrotic transformation can result from external compression of the uretero-pelvic junction by a tumor. Without timely intervention, this may lead to irreversible loss of renal parenchyma. Retroperitoneal liposarcoma is one potential cause of such compression. This article presents a clinical case highlighting the progression of the condition and explores surgical treatment options. Special emphasis is placed on evaluating various operative approaches. Comparative analysis indicates that laparoscopic nephrectomy combined with complete resection of the liposarcoma with negative surgical margins remains the preferred strategy, as it is associated with improved patient survival outcomes.