Serine/Arginine protein kinase inhibitors potentiate melanoma cell death and metastatic inhibition through apoptotic protein triggering and vimentin dysregulation
SRPK inhibitors potentially suppressed melanoma cell survivability and metastasis through the triggering of apoptotic proteins and dysregulating vimentin. These collected data serve as a basis for utilizing new alternative therapeutic strategies by targeting splicing regulator SRPK, for melanoma treatment.
Authors
- Jesadagorn Siriwath
- Atit Silsirivanit (ORCID: https://orcid.org/0000-0002-5777-3843)
- Sukanya Horpaopan (ORCID: https://orcid.org/0000-0001-5353-0409)
- Worasak Kaewkong (ORCID: https://orcid.org/0000-0002-7130-5827)
- Chaturong Inpad (ORCID: https://orcid.org/0000-0002-4173-5893)
- Sittiruk Roytrakul (ORCID: https://orcid.org/0000-0003-3696-8390)
- Kanyanut Kotanart
Institutions
- Khon Kaen University (TH)
- Chiang Mai University (TH)
- Naresuan University (TH)
- National Center for Genetic Engineering and Biotechnology (TH)
Publication Details
- Journal
- Advanced Pharmaceutical Bulletin
- Published
- 2025-07-19
- DOI
- https://doi.org/10.34172/apb.025.43291
- Primary Topic
- RNA Interference and Gene Delivery
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Khon Kaen University
- Naresuan University