Heavy bleeding after biopsy of nasopharyngeal juvenile angiofibroma

Juvenile nasopharyngeal angiofibroma (JNA) is a benign but locally aggressive vascular tumor that affects young males. Biopsy of this highly vascularized lesion is inadvisable. This case illustrates a patient with JNA who underwent a biopsy, resulting in severe bleeding, highlighting the importance of differentiating JNA from more common conditions with similar symptoms. A multidisciplinary approach is essential, and endoscopic resection is the cornerstone of treatment, often involving preoperative MRI with angiography and embolisation to minimise blood loss and improve outcomes.

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Publication Details

Journal
Ugeskrift for Læger
Published
2025-07-14
DOI
https://doi.org/10.61409/v11240797
Primary Topic
Head and Neck Surgical Oncology
Type
article
Field-Weighted Citation Impact
0.00

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article

Heavy bleeding after biopsy of nasopharyngeal juvenile angiofibroma

Peter Bill Juul Ladegaard, P Darling, Maria Inês Leite
Ugeskrift for Læger
Head and Neck Surgical Oncology
article

Heavy bleeding after biopsy of nasopharyngeal juvenile angiofibroma

Peter Bill Juul Ladegaard, P Darling, Maria Inês Leite
article en

Abstract

Juvenile nasopharyngeal angiofibroma (JNA) is a benign but locally aggressive vascular tumor that affects young males. Biopsy of this highly vascularized lesion is inadvisable. This case illustrates a patient with JNA who underwent a biopsy, resulting in severe bleeding, highlighting the importance of differentiating JNA from more common conditions with similar symptoms. A multidisciplinary approach is essential, and endoscopic resection is the cornerstone of treatment, often involving preoperative MRI with angiography and embolisation to minimise blood loss and improve outcomes.

Ugeskrift for LægerVol. 187(29)
Odense University Hospital (DK), Hospital South West Jutland (DK)
Odense Universitetshospital
Good health and well-being
Openalex Percentile: Top 68%
Head and Neck Surgical Oncology
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