Metabolomic stratification of shock: pathophysiological insights for personalized critical care
Shock patients exhibit distinct metabolic phenotypes associated with clinical severity and outcomes. Metabolomic profiling offers a promising avenue for precision medicine in critical care by uncovering pathophysiological insights. Future research should validate these findings, identify practical biomarkers, and explore therapeutic interventions tailored to specific metabolic profiles.
Authors
- Antoine Herpain (ORCID: https://orcid.org/0000-0002-0981-0208)
- Frederic Sangla
- Karim Bendjelid (ORCID: https://orcid.org/0000-0002-7921-7207)
- Federico Aletti (ORCID: https://orcid.org/0000-0003-1472-837X)
- Vicent Ribas (ORCID: https://orcid.org/0000-0003-3380-2256)
- David Legouis (ORCID: https://orcid.org/0000-0002-2924-9737)
- Bernardo Bollen Pinto (ORCID: https://orcid.org/0000-0002-1281-543X)
Institutions
- University of Geneva (CH)
- Université Libre de Bruxelles (BE)
- Hospital Israelita Albert Einstein (BR)
- Technological Center of Nutrition and Health (ES)
- University Hospital of Geneva (CH)
- Centre Hospitalier Universitaire de Saint-Pierre (BE)
Publication Details
- Journal
- Annals of Intensive Care
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1186/s13613-025-01532-1
- Citations
- 3
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 4.06
Funders
- European Commission
- Université de Genève