Unveiling CTRB2, RSPO3, KLOTB, and ROR1 as obesity-pancreatic disease association proteins: a comprehensive Mendelian randomization study
The MR suggests that circulating CTRB2, RSPO3, KLOTB, and ROR1 proteins may mediate associations between obesity and pancreatic diseases.
Authors
- Xue Li (ORCID: https://orcid.org/0000-0001-6880-2577)
- Xiaocang Cao (ORCID: https://orcid.org/0000-0001-8376-3481)
- Jie Chen (ORCID: https://orcid.org/0000-0002-4029-4192)
- Jie Zheng (ORCID: https://orcid.org/0000-0002-6623-6839)
- Shuai Yuan (ORCID: https://orcid.org/0000-0001-5055-5627)
- Xixian Ruan (ORCID: https://orcid.org/0000-0002-4937-9168)
- Chunhua Zhou (ORCID: https://orcid.org/0000-0003-2351-578X)
- Duowu Zou (ORCID: https://orcid.org/0000-0002-2461-5304)
- Xiaoyan Wang (ORCID: https://orcid.org/0000-0002-7281-1078)
- Yao Zhang (ORCID: https://orcid.org/0000-0001-5858-6225)
- Tianyi Che (ORCID: https://orcid.org/0009-0007-1402-9583)
Institutions
- Central South University (CN)
- Ruijin Hospital (CN)
- Tianjin Medical University General Hospital (CN)
- Karolinska Institutet (SE)
- Third Xiangya Hospital (CN)
- Second Affiliated Hospital of Zhejiang University (CN)
Publication Details
- Journal
- Gastroenterology report
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1093/gastro/goaf057
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China