Inducing Thrombotic Stroke Through Hypoxia and Ischemia in a Mouse Model

Source: Sun, Y. Y., et al., A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia. J. Vis. Exp. (2015).` This video demonstrates the procedure of replicating a thrombotic stroke in a mouse model by blocking the right common carotid artery and exposing the mouse to a low-oxygen environment. This process reduces blood and oxygen flow to the brain, causing blood clot formation and brain damage.