Induction of Levodopa-Induced Dyskinesias in a Rat Model of Parkinson's Disease

Source: Caulfield, M. E., et al. Induction and Assessment of Levodopa-induced Dyskinesias in a Rat Model of Parkinson's Disease. J. Vis. Exp. (2021). This video demonstrates the process of inducing levodopa-induced dyskinesias in a Parkinson's rat model by administering levodopa alongside a dopamine conversion inhibitor. Repeated injections overstimulate the brain neurons, resulting in motor dysfunction.

Publication Details

Journal: Journal of Visualized Experiments
Published: 2025-07-24
DOI: https://doi.org/10.3791/31382
Primary Topic: Neuroscience and Neuropharmacology Research
Type: article
Field-Weighted Citation Impact: 0.00

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article

Induction of Levodopa-Induced Dyskinesias in a Rat Model of Parkinson's Disease

Jul 24, 2025

Journal of Visualized Experiments

Neuroscience and Neuropharmacology Research

article

Induction of Levodopa-Induced Dyskinesias in a Rat Model of Parkinson's Disease

July 24, 2025article en

Abstract

Journal of Visualized Experiments

Openalex Percentile: Top 80%

Neuroscience and Neuropharmacology Research

DOI Source OpenAlex

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Induction of Levodopa-Induced Dyskinesias in a Rat Model of Parkinson's Disease · Journal of Visualized Experiments (2025) | TGRS Research Map | TGRS