Studying the Excitability of Fluorescent Neurons using a Whole-Cell Patch Clamp

Source: Briz, C. G., et al., In Utero Electroporation Approaches to Study the Excitability of Neuronal Subpopulations and Single-cell Connectivity. J. Vis. Exp. (2017) The video demonstrates a method to study the excitability of neuronal cells expressing fluorescent protein using a whole-cell patch current clamp. In the current-clamp mode, action potentials indicative of neuronal excitability are generated.