A Method to Inflict Closed Head Traumatic Brain Injury in <em>Drosophila</em>

Source: Katzenberger, R. J., et al., A Method to Inflict Closed Head Traumatic Brain Injury in Drosophila. J. Vis. Exp. (2015). The video demonstrates the use of a High-Impact Trauma (HIT) device to induce closed-head traumatic brain injury (TBI) in Drosophila. TBI causes mechanical brain trauma affecting neuronal function, which over time leads to neurodegeneration and mortality.