Monitoring the Brain Cortex with a Multi-Electrode Array in Response to Seizure-Inducing Agents

Source: Lu, H. C., et al. Direct-current stimulation and multi-electrode array recording of seizure-like activity in mice brain slice preparation. J. Vis. Exp. (2016). In this video, the effects of transcranial direct-current stimulation (tDCS) on brain slices containing the anterior cingulate cortex (ACC) and thalamus regions are investigated, using a multi-electrode array (MEA) to measure electric signals. By delivering electric pulses and infusing seizure-inducing drugs, the study investigates the ACC response to seizures.