A Viral Vector Injection into the Rat Substantia Nigra for Neurodegenerative Disease Modeling

Source: Van der Perren, A. et al., Development of an Alpha-synuclein Based Rat Model for Parkinson's Disease via Stereotactic Injection of a Recombinant Adeno-associated Viral Vector. J. Vis. Exp.  (2016). This video demonstrates the process of injecting a viral vector into the rat substantia nigra to model Parkinson's disease. It outlines the steps for preparing the rat, microinjecting the viral vector into the substantia nigra, and the recovery procedure.