Electrophysiological Recording from Colonic Afferent Nerves in an Ex Vivo Rat Colon

Source: Meng, Y. et al., In Vitro Characterization of the Electrophysiological Properties of Colonic Afferent Fibers in Rats. J. Vis. Exp. (2017) This video demonstrates a method to record the activity of colonic afferent nerves in an ex-vivo rat colon, cannulated at both ends and infused with saline to increase intraluminal pressure. As pressure increases, the nerve signal rises, indicating its stimulation.

Publication Details

Journal
Journal of Visualized Experiments
Published
2025-07-24
DOI
https://doi.org/10.3791/31239
Primary Topic
Gastrointestinal motility and disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Electrophysiological Recording from Colonic Afferent Nerves in an Ex Vivo Rat Colon

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Journal of Visualized Experiments
Gastrointestinal motility and disorders
article

Electrophysiological Recording from Colonic Afferent Nerves in an Ex Vivo Rat Colon

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Abstract

Source: Meng, Y. et al., In Vitro Characterization of the Electrophysiological Properties of Colonic Afferent Fibers in Rats. J. Vis. Exp. (2017) This video demonstrates a method to record the activity of colonic afferent nerves in an ex-vivo rat colon, cannulated at both ends and infused with saline to increase intraluminal pressure. As pressure increases, the nerve signal rises, indicating its stimulation.

Journal of Visualized Experiments
Openalex Percentile: Top 71%
Gastrointestinal motility and disorders
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Electrophysiological Recording from Colonic Afferent Nerves in an Ex Vivo Rat Colon · Journal of Visualized Experiments (2025) | TGRS Research Map | TGRS