Recording Synaptic Currents at the <em>Drosophila</em> Larval Neuromuscular Junction

Source: Vasin, A., et al. Focal Macropatch Recordings of Synaptic Currents from the Drosophila Larval Neuromuscular Junction. J. Vis. Exp. (2017) This video demonstrates the technique for recording synaptic currents from a synaptic bouton at the Drosophila larva's neuromuscular junction. This technique enables monitoring the activity of a single synaptic bouton, which is important for the study of mutant fly lines with enhanced spontaneous or asynchronous synaptic activity.