Triggering and Monitoring Heat-Induced Seizures in a Transgenic Mouse Model

Source: Das, A., et al. A Behavioral Screen for Heat-Induced Seizures in Mouse Models of Epilepsy. J. Vis. Exp. (2021) This video demonstrates the procedure to induce heat-induced seizures in a transgenic mouse with epilepsy-related gene mutations by gradually increasing body temperature in a controlled chamber. This protocol is used to study seizure mechanisms and potential therapies for epilepsy.

Publication Details

Journal
Journal of Visualized Experiments
Published
2025-07-24
DOI
https://doi.org/10.3791/31389
Primary Topic
Adipose Tissue and Metabolism
Type
article
Field-Weighted Citation Impact
0.00
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article

Triggering and Monitoring Heat-Induced Seizures in a Transgenic Mouse Model

Journal of Visualized Experiments
Adipose Tissue and Metabolism
article

Triggering and Monitoring Heat-Induced Seizures in a Transgenic Mouse Model

article en

Abstract

Source: Das, A., et al. A Behavioral Screen for Heat-Induced Seizures in Mouse Models of Epilepsy. J. Vis. Exp. (2021) This video demonstrates the procedure to induce heat-induced seizures in a transgenic mouse with epilepsy-related gene mutations by gradually increasing body temperature in a controlled chamber. This protocol is used to study seizure mechanisms and potential therapies for epilepsy.

Journal of Visualized Experiments
Openalex Percentile: Top 76%
Adipose Tissue and Metabolism
DOISourceOpenAlex
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Triggering and Monitoring Heat-Induced Seizures in a Transgenic Mouse Model · Journal of Visualized Experiments (2025) | TGRS Research Map | TGRS