Studying the Effect of Pesticides on <em>Caenorhabditis elegans</em> Neurons

Source: Susman, K. M. R. Examining the Effect of Pesticides on Caenorhabditis elegans Neurons. J. Vis. Exp. (2022). This video demonstrates evaluating the neurodegenerative effects of a test chemical on Caenorhabditis elegans with fluorescently tagged neurons. Normal neurons show bright fluorescence of intact soma and processes, while diminished fluorescence, swollen soma, and punctuated processes indicate neurodegeneration.

Publication Details

Journal
Journal of Visualized Experiments
Published
2025-07-24
DOI
https://doi.org/10.3791/31327
Primary Topic
Genetics, Aging, and Longevity in Model Organisms
Type
article
Field-Weighted Citation Impact
0.00
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article

Studying the Effect of Pesticides on Caenorhabditis elegans Neurons

Journal of Visualized Experiments
Genetics, Aging, and Longevity in Model Organisms
article

Studying the Effect of Pesticides on Caenorhabditis elegans Neurons

article en

Abstract

Source: Susman, K. M. R. Examining the Effect of Pesticides on Caenorhabditis elegans Neurons. J. Vis. Exp. (2022). This video demonstrates evaluating the neurodegenerative effects of a test chemical on Caenorhabditis elegans with fluorescently tagged neurons. Normal neurons show bright fluorescence of intact soma and processes, while diminished fluorescence, swollen soma, and punctuated processes indicate neurodegeneration.

Journal of Visualized Experiments
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Genetics, Aging, and Longevity in Model Organisms
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Studying the Effect of Pesticides on <em>Caenorhabditis elegans</em> Neurons · Journal of Visualized Experiments (2025) | TGRS Research Map | TGRS