Inducing Local Demyelination in the Optic Nerve Using Lysolecithin

Source: You, Y. et al., Visual Evoked Potential Recording in a Rat Model of Experimental Optic Nerve Demyelination. J. Vis. Exp. (2015) This video demonstrates the procedure of surgically accessing the optic nerve in an anesthetized animal and precisely delivering lysolecithin to induce focal demyelination, creating neuropathological conditions for further study.

Publication Details

Journal: Journal of Visualized Experiments
Published: 2025-07-24
DOI: https://doi.org/10.3791/31331
Primary Topic: Research on Leishmaniasis Studies
Type: article
Field-Weighted Citation Impact: 0.00

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article

Inducing Local Demyelination in the Optic Nerve Using Lysolecithin

Jul 24, 2025

Journal of Visualized Experiments

Research on Leishmaniasis Studies

article

Inducing Local Demyelination in the Optic Nerve Using Lysolecithin

July 24, 2025article en

Abstract

Journal of Visualized Experiments

Openalex Percentile: Top 74%

Research on Leishmaniasis Studies

DOI Source OpenAlex

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Inducing Local Demyelination in the Optic Nerve Using Lysolecithin · Journal of Visualized Experiments (2025) | TGRS Research Map | TGRS