Induction of Cerebral Microhemorrhages in a Rat Model Using Lipopolysaccharide
Source: Li, D., et al. Sub-acute Cerebral Microhemorrhages Induced by Lipopolysaccharide Injection in Rats. J. Vis. Exp. (2018). This video demonstrates the process of inducing blood-brain barrier (BBB) disruption and cerebral microhemorrhages in a rat model using lipopolysaccharide (LPS). It highlights the sequence of immune responses that lead to increased BBB permeability and subsequent brain tissue damage.
Publication Details
- Journal
- Journal of Visualized Experiments
- Published
- 2025-07-24
- DOI
- https://doi.org/10.3791/31342
- Primary Topic
- Intracerebral and Subarachnoid Hemorrhage Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00