Isolation of Amyloid Fibrils from Brain Tissue Extract

Source: Upadhyay, A. et al., Biochemical Purification and Proteomic Characterization of Amyloid Fibril Cores from the Brain. J. Vis. Exp. (2022) This video demonstrates the protocol for isolating  amyloid fibrils from mouse brain tissue extract using density gradient centrifugation and digestion of non-amyloid proteins.

Publication Details

Journal
Journal of Visualized Experiments
Published
2025-07-24
DOI
https://doi.org/10.3791/31306
Primary Topic
Supramolecular Self-Assembly in Materials
Type
article
Field-Weighted Citation Impact
0.00
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article

Isolation of Amyloid Fibrils from Brain Tissue Extract

Journal of Visualized Experiments
Supramolecular Self-Assembly in Materials
article

Isolation of Amyloid Fibrils from Brain Tissue Extract

article en

Abstract

Source: Upadhyay, A. et al., Biochemical Purification and Proteomic Characterization of Amyloid Fibril Cores from the Brain. J. Vis. Exp. (2022) This video demonstrates the protocol for isolating  amyloid fibrils from mouse brain tissue extract using density gradient centrifugation and digestion of non-amyloid proteins.

Journal of Visualized Experiments
Zero hunger
Openalex Percentile: Top 88%
Supramolecular Self-Assembly in Materials
DOISourceOpenAlex
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Isolation of Amyloid Fibrils from Brain Tissue Extract · Journal of Visualized Experiments (2025) | TGRS Research Map | TGRS