Utilizing Multielectrode Arrays to Measure Synaptic Physiology in 3D Coculture Spheres

Source: Cvetkovic, C., et al. Synaptic Microcircuit Modeling with 3D Cocultures of Astrocytes and Neurons from Human Pluripotent Stem Cells. J. Vis. Exp. (2018) This video demonstrates the procedure of using the multielectrode array (MEA) to measure synaptic physiology in 3D coculture spheres. This method allows to understand the neural network dynamics and synaptic network burst activity within the 3D spheres.

Publication Details

Journal: Journal of Visualized Experiments
Published: 2025-07-24
DOI: https://doi.org/10.3791/31182
Primary Topic: Plant and Biological Electrophysiology Studies
Type: article
Field-Weighted Citation Impact: 0.00

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article

Utilizing Multielectrode Arrays to Measure Synaptic Physiology in 3D Coculture Spheres

Jul 24, 2025

Journal of Visualized Experiments

Plant and Biological Electrophysiology Studies

article

Utilizing Multielectrode Arrays to Measure Synaptic Physiology in 3D Coculture Spheres

July 24, 2025article en

Abstract

Journal of Visualized Experiments

Openalex Percentile: Top 86%

Plant and Biological Electrophysiology Studies

DOI Source OpenAlex

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Utilizing Multielectrode Arrays to Measure Synaptic Physiology in 3D Coculture Spheres · Journal of Visualized Experiments (2025) | TGRS Research Map | TGRS