Establishing an Alzheimer's Disease Model in Zebrafish Brain Through Amyloid Peptide Injection

Bhattarai, P., et al. Modeling Amyloid-β42 Toxicity and Neurodegeneration in Adult Zebrafish Brain. J. Vis. Exp. (2017). This video demonstrates the procedure of injecting monomeric amyloid peptides into the forebrain of adult zebrafish to generate amyloid toxicity, mimicking the neuronal damage seen in Alzheimer's disease

Publication Details

Journal
Journal of Visualized Experiments
Published
2025-07-24
DOI
https://doi.org/10.3791/31350
Primary Topic
Zebrafish Biomedical Research Applications
Type
article
Field-Weighted Citation Impact
0.00
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article

Establishing an Alzheimer's Disease Model in Zebrafish Brain Through Amyloid Peptide Injection

Journal of Visualized Experiments
Zebrafish Biomedical Research Applications
article

Establishing an Alzheimer's Disease Model in Zebrafish Brain Through Amyloid Peptide Injection

article en

Abstract

Bhattarai, P., et al. Modeling Amyloid-β42 Toxicity and Neurodegeneration in Adult Zebrafish Brain. J. Vis. Exp. (2017). This video demonstrates the procedure of injecting monomeric amyloid peptides into the forebrain of adult zebrafish to generate amyloid toxicity, mimicking the neuronal damage seen in Alzheimer's disease

Journal of Visualized Experiments
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Openalex Percentile: Top 80%
Zebrafish Biomedical Research Applications
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Establishing an Alzheimer's Disease Model in Zebrafish Brain Through Amyloid Peptide Injection · Journal of Visualized Experiments (2025) | TGRS Research Map | TGRS