Treatment of Rat Coronal Slices with a Neurotoxic Peptide

Source: Brai, E., et al. An Alternative Approach to Study Primary Events in Neurodegeneration Using Ex Vivo Rat Brain Slices. J. Vis. Exp. (2018) This video demonstrates the procedure to prepare and treat rat brain hemislices with a neurotoxic peptide to mimic neurodegeneration. The protocol allows for analyzing neurodegenerative events by directly comparing control and treated slices in the same anatomical plane.

Publication Details

Journal
Journal of Visualized Experiments
Published
2025-07-24
DOI
https://doi.org/10.3791/31408
Primary Topic
Neuropeptides and Animal Physiology
Type
article
Field-Weighted Citation Impact
0.00
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article

Treatment of Rat Coronal Slices with a Neurotoxic Peptide

Journal of Visualized Experiments
Neuropeptides and Animal Physiology
article

Treatment of Rat Coronal Slices with a Neurotoxic Peptide

article en

Abstract

Source: Brai, E., et al. An Alternative Approach to Study Primary Events in Neurodegeneration Using Ex Vivo Rat Brain Slices. J. Vis. Exp. (2018) This video demonstrates the procedure to prepare and treat rat brain hemislices with a neurotoxic peptide to mimic neurodegeneration. The protocol allows for analyzing neurodegenerative events by directly comparing control and treated slices in the same anatomical plane.

Journal of Visualized Experiments
Good health and well-being
Openalex Percentile: Top 80%
Neuropeptides and Animal Physiology
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Treatment of Rat Coronal Slices with a Neurotoxic Peptide · Journal of Visualized Experiments (2025) | TGRS Research Map | TGRS