Recording CA3-CA1 Synaptic Responses in a Rat Hippocampal Slice

Source: Shetty, M. S. et al., Investigation of Synaptic Tagging/Capture and Cross-capture using Acute Hippocampal Slices from Rodents. J. Vis. Exp. (2015). This video demonstrates a method to record CA3-CA1 synaptic responses in a rat hippocampal slice. It outlines the steps involved in placing the stimulating and recording electrodes on the hippocampal slice and measuring the field excitatory postsynaptic potential (fEPSP) to assess synaptic response strength.