Injectable Mesh Electronics for Stable Single-Neuron Recordings in a Mouse Brain

Source: Schuhmann Jr., T. G., et al. Syringe-injectable Mesh Electronics for Stable Chronic Rodent Electrophysiology. J. Vis. Exp. (2018). The video demonstrates the injection of mesh electronics probes into a mouse brain for stable long-term recordings at a single-neuron level. An anesthetized mouse with an exposed skull is secured on a stereotaxic frame, and the probe's mesh device region is injected into the brain through drilled holes. The probe's input-output pads are connected to a circuit, and recordings are obtained using a data acquisition system.