Direct Reprogramming of Hematopoietic Progenitor Cells into Neural Stem Cells

Source: Wang, T., et al. Direct Induction of Human Neural Stem Cells from Peripheral Blood Hematopoietic Progenitor Cells. J. Vis. Exp, (2015) This video demonstrates the direct reprogramming of genetically modified hematopoietic progenitor cells into neuronal stem cells. Transcription factors expressed by hematopoietic progenitor cells trigger a cascade of molecular events facilitating their transformation. Further specific media is used to select and grow induced neuronal stem cells.

Publication Details

Journal
Journal of Visualized Experiments
Published
2025-07-24
DOI
https://doi.org/10.3791/31048
Primary Topic
Pluripotent Stem Cells Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Direct Reprogramming of Hematopoietic Progenitor Cells into Neural Stem Cells

Journal of Visualized Experiments
Pluripotent Stem Cells Research
article

Direct Reprogramming of Hematopoietic Progenitor Cells into Neural Stem Cells

article en

Abstract

Source: Wang, T., et al. Direct Induction of Human Neural Stem Cells from Peripheral Blood Hematopoietic Progenitor Cells. J. Vis. Exp, (2015) This video demonstrates the direct reprogramming of genetically modified hematopoietic progenitor cells into neuronal stem cells. Transcription factors expressed by hematopoietic progenitor cells trigger a cascade of molecular events facilitating their transformation. Further specific media is used to select and grow induced neuronal stem cells.

Journal of Visualized Experiments
Zero hunger
Openalex Percentile: Top 83%
Pluripotent Stem Cells Research
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Direct Reprogramming of Hematopoietic Progenitor Cells into Neural Stem Cells · Journal of Visualized Experiments (2025) | TGRS Research Map | TGRS