Initiating Rapid Neurite Extension and Formation Functional Neuronal Connections

Source: M. H. Magdesian et al., Rewiring Neuronal Circuits: A New Method for Fast Neurite Extension and Functional Neuronal Connection, J. Vis. Exp. (2017) This video demonstrates a technique for the rapid initiation and extension of a neuron and creation of new connections with a target neuron using a microfluidic device and micromanipulation. This could be used for therapies that aim to reconnect neuronal circuits after trauma or in neurodegenerative diseases.