Hemodialysis removes protective metabolites and disrupts mitochondrial function
Hemodialysis alters the plasma metabolome by removing toxins but also depleting protective metabolites and promoting lipotoxic intermediates. These shifts may undermine therapy benefits, highlighting the need for strategies that preserve metabolic homeostasis in dialysis patients.
Authors
- María Peris‐Fernández (ORCID: https://orcid.org/0000-0002-1299-5995)
- Amparo Soldevila-Orient
- Iris Viejo-Boyano (ORCID: https://orcid.org/0000-0003-2181-5068)
- Ramón Devesa-Such
- Marta Roca (ORCID: https://orcid.org/0000-0003-0708-6364)
- Julio Hernández Jaras (ORCID: https://orcid.org/0000-0003-1250-1550)
- Pilar Sánchez‐Pérez (ORCID: https://orcid.org/0000-0002-8026-5476)
Institutions
- Hospital Universitari i Politècnic La Fe (ES)
- Leitat Technological Center (ES)
Publication Details
- Journal
- Nephrology Dialysis Transplantation
- Published
- 2025-07-30
- DOI
- https://doi.org/10.1093/ndt/gfaf145
- Primary Topic
- Diet and metabolism studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00