Ubiquitin-specific peptidase 30-mediated deubiquitination of forkhead box O3 promotes the progression of subarachnoid hemorrhage by regulating cGAS/STING pathway
USP30-mediated deubiquitination of FOXO3 contributed to OxyHb-induced microglia inflammation, M1 polarization, and pyroptosis, providing a novel target for the treatment of SAH.
Authors
- Guiqiang Zhang (ORCID: https://orcid.org/0000-0002-7759-1983)
- Wenfeng Xu
Institutions
- The People's Hospital of Guangxi Zhuang Autonomous Region (CN)
- First Affiliated Hospital of GuangXi Medical University (CN)
- Riverside Hospital of Guangxi Zhuang Autonomous Region (CN)
Publication Details
- Journal
- Neuroreport
- Published
- 2025-07-14
- DOI
- https://doi.org/10.1097/wnr.0000000000002192
- Primary Topic
- Ubiquitin and proteasome pathways
- Type
- article
- Field-Weighted Citation Impact
- 0.00