Multifaceted Cooperation Between WNT and PI3K Signaling Axis through the Long Noncoding RNA SNHG16 and TCF7 in de novo Acute Lymphoblastic Leukemia Patients.
Our findings demonstrate that SNHG16 and TCF7 lncRNA may act as crucial regulators of the Akt and β-catenin in ALL, which in turn influence c-Myc expression levels in affected individuals. Further research is needed to better understand the molecular mechanisms underlying ALL, potentially leading to improved treatment and monitoring strategies for patients.
Authors
- Mohammad Sayyadi (ORCID: https://orcid.org/0000-0003-2927-9669)
- Maryam Khani (ORCID: https://orcid.org/0009-0002-9385-4349)
- Atbin Latifi
Institutions
- Arak University of Medical Sciences (IR)
Publication Details
- Journal
- PubMed
- Published
- 2025-05-01
- DOI
- https://doi.org/10.61186/ibj.5031
- Citations
- 1
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 0.94