Multifaceted Cooperation Between WNT and PI3K Signaling Axis through the Long Noncoding RNA SNHG16 and TCF7 in de novo Acute Lymphoblastic Leukemia Patients.

Our findings demonstrate that SNHG16 and TCF7 lncRNA may act as crucial regulators of the Akt and β-catenin in ALL, which in turn influence c-Myc expression levels in affected individuals. Further research is needed to better understand the molecular mechanisms underlying ALL, potentially leading to improved treatment and monitoring strategies for patients.

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Publication Details

Journal
PubMed
Published
2025-05-01
DOI
https://doi.org/10.61186/ibj.5031
Citations
1
Primary Topic
Cancer-related molecular mechanisms research
Type
article
Field-Weighted Citation Impact
0.94
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article

Multifaceted Cooperation Between WNT and PI3K Signaling Axis through the Long Noncoding RNA SNHG16 and TCF7 in de novo Acute Lymphoblastic Leukemia Patients.

Mohammad Sayyadi, Maryam Khani, Atbin Latifi
1 citations
PubMed
Cancer-related molecular mechanisms research
0.94
article

Multifaceted Cooperation Between WNT and PI3K Signaling Axis through the Long Noncoding RNA SNHG16 and TCF7 in de novo Acute Lymphoblastic Leukemia Patients.

Mohammad Sayyadi, Maryam Khani, Atbin Latifi
article en
1 citations

Abstract

Our findings demonstrate that SNHG16 and TCF7 lncRNA may act as crucial regulators of the Akt and β-catenin in ALL, which in turn influence c-Myc expression levels in affected individuals. Further research is needed to better understand the molecular mechanisms underlying ALL, potentially leading to improved treatment and monitoring strategies for patients.

PubMedVol. 29(3)
Arak University of Medical Sciences (IR)
Openalex Percentile: Top 22%
Cancer-related molecular mechanisms research
0.94
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