Disulfidptosis-Related Genes as Novel Biomarkers and Therapeutic Targets in Dilated Cardiomyopathy.
This study demonstrates that ACTN4, MYH10, TLN1, DSTN, and NCKAP1 play significant roles in the pathogenesis of DCM, influencing immune cell infiltration and metabolic homeostasis. Quercetin and resveratrol were identified as potential therapeutic agents, offering new directions for DCM treatment.
Authors
- Yafeng Zhou (ORCID: https://orcid.org/0009-0005-2606-3776)
- Huimin Fan (ORCID: https://orcid.org/0009-0004-5530-974X)
- Pinfang Kang (ORCID: https://orcid.org/0000-0001-7084-7862)
- Yiyao Zeng
- Anchen Xu (ORCID: https://orcid.org/0000-0001-5033-8518)
- Xiangyu Wang (ORCID: https://orcid.org/0000-0001-8074-0882)
- Xin Tan (ORCID: https://orcid.org/0009-0005-9741-6946)
- Hongju Wang (ORCID: https://orcid.org/0000-0002-1662-485X)
- Jili Fan
- Shuai Xu
- Xiaohong Bo
- Yangjun Fu
Institutions
- Soochow University (CN)
- Second Affiliated Hospital of Soochow University (CN)
- First Affiliated Hospital of Soochow University (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-01-01
- DOI
- https://doi.org/10.2147/jir.s525114
- Primary Topic
- Cardiac Fibrosis and Remodeling
- Type
- article
- Field-Weighted Citation Impact
- 0.00