Photobiomodulation for Degenerative Diseases: An Overview and Perspectives

<b><i>Background:</i></b> Photobiomodulation (PBM) is a well-established, noninvasive therapeutic modality supported by a robust scientific foundation and extensive case studies. <b><i>Objectives:</i></b> However, in recent years, researchers have reported that low-intensity light could also help slow down degenerative processes resulting from unbalanced or epigenetically exacerbated aging. <b><i>Methods:</i></b> We present data that support the use of PBM in addressing some of the primary degenerative diseases that significantly impact patients' quality of life. <b><i>Results:</i></b> Chronic diseases highlight the importance of emerging approaches utilizing low-power light sources, whether applied locally, systemically, or remotely. <b><i>Conclusions:</i></b> We conclude that PBM holds significant promise for patients suffering from chronic and debilitating conditions, offering potential therapeutic benefits. As the science of biophotonic continues to evolve, further advancements in light-based therapies are expected to enhance healing processes and improve the quality of life for patients worldwide. The growing body of evidence suggests that PBM is well-prepared to face the challenges imposed by degenerative diseases.