Optimal treatment duration in metastatic renal cell carcinoma patients responding to immune checkpoint inhibitors: should we treat beyond two years?
Among mRCC patients responding to ICPI, elective therapy discontinuation approximately 24 months after initiation does not appear to compromise outcomes compared to continuing therapy.
Authors
- Christof Vulsteke (ORCID: https://orcid.org/0000-0002-4607-5660)
- Marlies De Bock (ORCID: https://orcid.org/0000-0001-9439-9881)
- Alexander Decruyenaere (ORCID: https://orcid.org/0000-0001-6795-7606)
- Jolanda Verheezen
- Benoit Beuselinck (ORCID: https://orcid.org/0000-0001-7427-9102)
- Gennigens Christine
- Sylvie Rottey (ORCID: https://orcid.org/0000-0003-2060-3725)
- Emmanuel Seront (ORCID: https://orcid.org/0000-0003-4807-7472)
- Thomas Meyskens
- Peter Schatteman (ORCID: https://orcid.org/0000-0001-5709-5643)
- Annouschka Laenen (ORCID: https://orcid.org/0000-0002-1371-442X)
- Sandrine Aspeslagh (ORCID: https://orcid.org/0000-0001-6598-9161)
- Barbara Brouwers (ORCID: https://orcid.org/0000-0002-5036-1301)
- Julie Bastin (ORCID: https://orcid.org/0000-0001-8266-3008)
- Nieves Martínez Chanzá (ORCID: https://orcid.org/0000-0002-2340-7415)
- Philip R. Debruyne (ORCID: https://orcid.org/0000-0001-5438-9697)
- Daisy Luyten (ORCID: https://orcid.org/0009-0009-3917-7587)
- Els Everaert (ORCID: https://orcid.org/0000-0002-8874-6602)
- Heidi Van den Bulck
- Verbiest Annelies
Institutions
- Cliniques Universitaires Saint-Luc (BE)
- University of Antwerp (BE)
- University of Liège (BE)
- AZ Groeninge (BE)
- Ghent University Hospital (BE)
- Institut Jules Bordet (BE)
- Statistics Belgium (BE)
- AZ Klina (BE)
- Jessa Hospital (BE)
- Onze Lieve Vrouwziekenhuis Hospital (BE)
- Antwerp University Hospital (BE)
- Province of Antwerp (BE)
- AZ Sint-Jan (BE)
- Vlaamse Vereniging voor Obstetrie en Gynaecolo (BE)
- Centre Hospitalier Universitaire de Liège (BE)
- Imelda Hospital (BE)
- Groene Hart Ziekenhuis (NL)
- AZ Maria Middelares (BE)
- AZ Delta (BE)
- Ziekenhuisnetwerk Antwerpen Stuivenberg (BE)
- Anglia Ruskin University (GB)
- University of Plymouth (GB)
- Mathys (Netherlands) (NL)
- KU Leuven (BE)
Publication Details
- Journal
- Acta Oncologica
- Published
- 2025-07-30
- DOI
- https://doi.org/10.2340/1651-226x.2025.43876
- Citations
- 1
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 1.05
Funders
- Fonds Wetenschappelijk Onderzoek
- Vlaamse regering