Hydrożelowe okłady łagodzące objawy migreny

Migraine is a chronic neurological disorder that directly affects up to one billion people worldwide. Current treatments for migraine involve acute treatment, including the use of analgesics, nonsteroidal anti-inflammatory drugs, triptans, and preventive treatment. One of the currently available solution relieving migraine symptoms is hydrogel patches. They typically provide a cooling effect due to the presence of an active substance, most commonly menthol. Unfortunately, despite menthol's undeniable advantages in cooling applications, its intense smell may be irritating for people with migraines, who suffer from olfactory hypersensitivity. Therefore, the following work proposes a novel solution that combines the benefits of hydrogels with a natural extract of feverfew, which is described in the literature as effective in relieving headaches, including migraines. In this study, hydrogel patches were developed based on a natural polymer and modified with feverfew extract. The physicochemical properties of the resulting materials were investigated, including swelling behavior, surface wettability, and substance release from the polymer matrix. The potential for use in the intended application was preliminarily assessed as possible, but requiring further studies.

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Publication Details

Journal
Wiadomości Chemiczne
Published
2025-01-01
DOI
https://doi.org/10.53584/wiadchem.2025.07.6
Primary Topic
Advanced Glycation End Products research
Type
article
Field-Weighted Citation Impact
0.00
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article

Hydrożelowe okłady łagodzące objawy migreny

Edyta Piłat, Justyna Kucińska‐Lipka, Przemysław Gnatowski, Natalia Krysiak et al.
Wiadomości Chemiczne
Advanced Glycation End Products research
article

Hydrożelowe okłady łagodzące objawy migreny

Edyta Piłat, Justyna Kucińska‐Lipka, Przemysław Gnatowski, Natalia Krysiak, Pola Gawrycka
article en

Abstract

Migraine is a chronic neurological disorder that directly affects up to one billion people worldwide. Current treatments for migraine involve acute treatment, including the use of analgesics, nonsteroidal anti-inflammatory drugs, triptans, and preventive treatment. One of the currently available solution relieving migraine symptoms is hydrogel patches. They typically provide a cooling effect due to the presence of an active substance, most commonly menthol. Unfortunately, despite menthol's undeniable advantages in cooling applications, its intense smell may be irritating for people with migraines, who suffer from olfactory hypersensitivity. Therefore, the following work proposes a novel solution that combines the benefits of hydrogels with a natural extract of feverfew, which is described in the literature as effective in relieving headaches, including migraines. In this study, hydrogel patches were developed based on a natural polymer and modified with feverfew extract. The physicochemical properties of the resulting materials were investigated, including swelling behavior, surface wettability, and substance release from the polymer matrix. The potential for use in the intended application was preliminarily assessed as possible, but requiring further studies.

Wiadomości ChemiczneVol. 79(7-8)
Gdańsk University of Technology (PL)
Openalex Percentile: Top 78%
Advanced Glycation End Products research
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