Nitric Oxide Resistance Linked to Vascular and Myocardial Dysfunction in Insulin Resistant Obese Children: A Novel Aortic Strain Study
Vascular dysfunction seen in obesity is probably orchestrated by a state of resistance to nitric oxide, induced by hyperinsulinemia. This vascular dysfunction seems to play a major role in reducing myocardial functions, especially the subendocardial component, which is known to be affected by impaired blood supply.
Authors
- Marwa Farouk Mira (ORCID: https://orcid.org/0000-0002-1930-6742)
- Antoine AbdelMassih (ORCID: https://orcid.org/0000-0001-8876-3229)
- Raghda Fouda (ORCID: https://orcid.org/0000-0001-6436-6093)
- Fatma Mostafa (ORCID: https://orcid.org/0000-0002-1222-0479)
- Noha Ali (ORCID: https://orcid.org/0000-0002-2447-2876)
- Sherif Abdel-Raouf
- Marianne Edward Yassa
Institutions
- Cairo University (EG)
- Shaikh Khalifa Medical City (AE)
- Cairo University hospitals (EG)
Publication Details
- Journal
- Journal of Cardiovascular Echography
- Published
- 2025-04-01
- DOI
- https://doi.org/10.4103/jcecho.jcecho_3_25
- Primary Topic
- Cardiovascular Health and Disease Prevention
- Type
- article
- Field-Weighted Citation Impact
- 0.00