Systemic inflammatory response index mediates the association between stroke and hypertension: a cross-sectional study from NHANES 2001 to 2016
Hypertension, SIRI, and stroke were closely related, with SIRI partially mediating their association, particularly in males. SIRI might be potential as a biomarker and therapeutic target for stroke prevention in hypertensive individuals.
Authors
- Tiezhu Wang (ORCID: https://orcid.org/0000-0003-4463-899X)
- Junyang Xu
- Yaxian Dong (ORCID: https://orcid.org/0009-0000-1841-3303)
- Feiyang Diao (ORCID: https://orcid.org/0000-0003-0118-3382)
- Xiulan Lai (ORCID: https://orcid.org/0000-0002-2764-8937)
- Jinxi Zuo (ORCID: https://orcid.org/0000-0002-2188-1543)
- Jianpeng Lin (ORCID: https://orcid.org/0000-0001-6766-431X)
- Mingzhu Tang
- Xiaolian Chen (ORCID: https://orcid.org/0000-0003-2067-0979)
- Hongting Shi
- Lihua Yang (ORCID: https://orcid.org/0000-0002-6801-0382)
Institutions
- Second Affiliated Hospital of Guangzhou Medical University (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2025-07-30
- DOI
- https://doi.org/10.3389/fneur.2025.1603241
- Citations
- 2
- Primary Topic
- Blood Pressure and Hypertension Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.78
Funders
- Foshan Science and Technology Bureau