<scp>APOE4</scp> Exacerbates Cerebral Tau Pathology Through Cholesterol‐Induced Degradation of Phosphatase in Atherosclerosis
Altogether, these results suggested a role of the APOE4 in linking AS with Tau neuropathology, which might increase the risk of related neurodegenerative diseases for AS patients.
Authors
- Cihang Gu
- Yang Gao (ORCID: https://orcid.org/0000-0003-1707-9053)
- Baofei Sun (ORCID: https://orcid.org/0000-0002-7003-6119)
- Li Wang (ORCID: https://orcid.org/0000-0001-8432-9986)
- Jian Zhang (ORCID: https://orcid.org/0000-0001-5703-7590)
- Bing Xia (ORCID: https://orcid.org/0000-0003-3259-6139)
- Jie Zheng (ORCID: https://orcid.org/0000-0003-1817-6357)
Institutions
- Guiyang Medical University (CN)
- Wuhan University (CN)
- Ministry of Education (ME)
- Zhongnan Hospital of Wuhan University (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- CNS Neuroscience & Therapeutics
- Published
- 2025-07-30
- DOI
- https://doi.org/10.1111/cns.70536
- Citations
- 5
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 5.82
Funders
- National Natural Science Foundation of China
- Department of Education of Guizhou Province