Genetic variants in the <scp><i>CD59</i></scp> gene: An exploratory study of large genome databases
We collated a list of CD59 variants, which were classified as neutral or deleterious by PredictSNP, from genome databases. These results can be applied to identify individuals with possible latent CD59 deficiency symptoms, such as hemolytic transfusion reactions. In conjunction with clinical data, these CD59 variants can guide personalized clinical decisions.
Authors
- Willy A. Flegel (ORCID: https://orcid.org/0000-0002-1631-7198)
- Kshitij Srivastava (ORCID: https://orcid.org/0000-0002-3658-0815)
- Thomas Christopher Recupero
Institutions
- National Institutes of Health Clinical Center (US)
Publication Details
- Journal
- Transfusion
- Published
- 2025-07-30
- DOI
- https://doi.org/10.1111/trf.18331
- Primary Topic
- Genomics and Rare Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- NIH Clinical Center