Huatan Tongmai Yin regulates RFRP-3 to intervene in the “microbe-gut-HPO axis” to treat PCOS-IR rats
Tantongmai Decoction can correct the imbalance of intestinal flora, improve intestinal mucosal barrier function, relieve chronic inflammation and insulin resistance, thus up-regulating RFRP-3 in the hypothalamus, inhibiting the release of GnRH and KP, reducing the secretion of LH and T, and effectively alleviating PCOS-IR by regulating "microbe-gut-HPO axis".
Authors
- Hanmei Lin (ORCID: https://orcid.org/0009-0009-3199-4224)
Institutions
- The First Affiliated Hospital of Guangxi University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- American Journal of Translational Research
- Published
- 2025-01-01
- DOI
- https://doi.org/10.62347/xgfs9323
- Primary Topic
- Dermatology and Skin Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Guangxi University