Elevated TXNIP and reduced PINK1 in gestational diabetes mellitus: association with dyslipidemia and pregnancy complications

Dyslipidemia in GDM-characterized by elevated TC, TG, and LDL-C and decreased HDL-C-may be associated with upregulation of TXNIP and downregulation of PINK1. These molecular alterations could contribute to metabolic disturbances and poor pregnancy outcomes. Monitoring lipid profiles alongside TXNIP and PINK1 expression may aid in the clinical management of GDM and its complications.